原著論文

・Suzuki KI, Isoyama Y, Kashiwagi K, Sakuma T, Ochiai H, Furuno N, Kashiwagi A and Yamamoto T. High efficiency TALENs enable F0 functional analysis by targeted gene disruption in Xenopus laevis embryos. Biology Open, in press (2013)

・Mashimo T, Kaneko T, Sakuma T, Kobayashi J, Kunihiro Y, Voigt B, Yamamoto T and Serikawa T. Efficient gene targeting by TAL effector nucleases coinjected with exonucleases in zygotes. Scientific Reports, 3, 1253 (2013)

・Hisano Y, Ota S, Arakawa S, Muraki M, Kono N, Oshita K, Sakuma T, Tomita M, Yamamoto T, Okada Y and Kawahara A. Quantitative assay for TALEN activity at endogenous genomic loci. Biology Open, 2(4):363-367 (2013)

・Ansai S, Sakuma T, Yamamoto T, Ariga H, Uemura N, Takahashi R, Kinoshita M. Efficient targeted mutagenesis in medaka using custom-designed transcription activator-like effector nucleases (TALENs). Genetics, 193(3): 739-749 (2013)

・Sakuma T, Hosoi S, Woltjen K, Suzuki KI, Kashiwagi K, Wada H, Ochiai H, Miyamoto T, Kawai N, Sasakura Y, Matsuura S, Okada Y, Kawahara A, Hayashi S and Yamamoto T. Efficient TALEN construction and evaluation methods for human cell and animal applications. Genes Cells, 18(4): 315-326 (2013)

・Mashimo T, Takizawa A, Kobayashi J, Kunihiro Y, Yoshimi K, Ishida S, Tanabe K, Yanagi A, Tachibana A, Hirose J, Yomoda J, Morimoto S, Kuramoto T, Voigt B, Watanabe T, Hiai H, Tateno C, Komatsu K, Serikawa T. Generation and Characterization of Severe Combined Immunodeficiency Rats. Cell Reports, 2(3):685-694 (2012)

・Nishizawa-Yokoi A, Nonaka S, Saika H, Kwon YI, Osakabe K and Toki S. Suppression of Ku70/80 or Lig4 leads to decreased stable transformation and enhanced homologous recombination in rice. New Phytol. 196(4): 1048-59 (2012)

・Kwon YI, Abe K, Osakabe K, Endo M, Nishizawa-Yokoi A, Saika H, Shimada H and Toki S. Overexpression of OsRecQl4 and/or OsExo1 Enhances DSB-Induced Homologous Recombination in Rice. Plant Cell Physiol. 53(12): 2142-52 (2012)

・Watanabe T, Ochiai H, Sakuma T, Horch H, Hamaguchi N, Nakamura T, Bando T, Ohuchi H, Yamamoto T, Noji S and Mito T. Non-transgenic genome modifications in a hemimetabolous insect using zinc-finger and TAL effector nucleases. Nat Commun. 3: 1017 (2012)

・Ochiai H, Sakamoto N, Fujita K, Nishikawa M, Suzuki KI, Matsuura S, Miyamoto T, Sakuma T, Shibata T, Yamamoto T. Zinc-finger nuclease-mediated targeted insertion of reporter genes for quantitative imaging of gene expression in sea urchin embryos. Proc Natl Acad Sci U S A. 109(27): 10915-10920 (2012)

・Kawai N, Ochiai H, Sakuma T, Yamada L, Sawada H, Yamamoto T, Sasakura Y. Efficient targeted mutagenesis of the chordate Ciona intestinalis genome with zinc-finger nucleases. Dev Growth Differ. 54(5): 535-545 (2012)

・Ansai S, Ochiai H, Kanie Y, Kamei Y, Gou Y, Kitano T, Yamamoto T, Kinoshita M. Targeted disruption of exogenous EGFP gene in medaka using zinc-finger nucleases. Dev Growth Differ. 54(5): 546-556 (2012)

・Mashimo T, Takizawa A, Voigt B, Yoshimi K, Hiai H, Kuramoto T, Serikawa T. Generation of knockout rats with X-linked severe combined immunodeficiency (X-SCID) using zinc-finger nucleases. PLoS One 5(1): e8870 (2010)

・Osakabe K, Osakabe Y, Toki S. Site-directed mutagenesis in Arabidopsis using custom-designed zinc finger nucleases. Proc Natl Acad Sci USA. 107(26):12034-12039 (2010)

・Ochiai H, Fujita K, Suzuki K, Nishikawa M, Shibata T, Sakamoto N, Yamamoto T. Targeted mutagenesis in the sea urchin embryo using zinc-finger nucleases. Genes Cells. 15(8):875-885 (2010)

総説

・ゲノム編集革命(監修：山本卓、野地澄晴）、細胞工学、Vol.32, No.5（2013）

・落合　博、佐久間哲史、松浦伸也、山本 卓：TLAEN nuclease (TALEN)を用いた培養細胞におけるゲノム編集、実験医学 Vol.31(1), p95-100（2013）

・佐久間哲史、坂本尚昭、山本 卓：人工ヌクレアーゼを用いたゲノム編集、Medical Science Digest Vol.38(8), p328-329（2012）

・真下知士、芹川忠夫：ジンクフィンガーヌクレアーゼ（ZFN）、細胞工学Vol.31(3),p296-301(2012)

・真下知士、芹川忠夫：ジンクフィンガーヌクレアーゼによる遺伝子改変動物の作製、Medical Science Digest Vol.38(1), p10-11（2012）

・刑部敬史、刑部祐里子、土岐精一：高等植物において特定の遺伝子だけを標的として破壊する技術、化学と生物　日本農芸化学会編、p592-594 (2011)

・刑部敬史、刑部祐里子、土岐精一：人工制限酵素を利用した高等植物における標的遺伝子改変技術の開発、バイオインダストリー　Vol.28(6)、p53-57 (2011)

・真下知士：新しい遺伝子改変技術「ジンクフィンガーヌクレアーゼ（ZFN）」、生物と化学、日本農芸化学会編、p220-222（2011）