七種　和美の業績リスト

学術論文


2017

1.Kato, D; Osakabe, A; Arimura, Y; Mizukami, Y; Horikoshi, N; Saikusa, K; Akashi, S; Nishimura, Y; Park, SY; Nogami, J; Maehara, K; Ohkawa, Y; Matsumoto, A; Kono, H; Inoue, R; Sugiyama, M; Kurumizaka, H.

“Crystal structure of the overlapping dinucleosome composed of hexasome and octasome”

SCIENCE, 356(6334), 205-208 (2017).


2015

2.Kazumi Saikusa, Shingo Shimoyama, Yuuki Asano, Aritaka Nagadoi, Mamoru Sato, Hitoshi Kurumizaka, Yoshifumi Nishimura, Satoko Akashi.
"Charge-neutralization effect of the tail regions on the histone H2A/H2B dimer structure."
Protein Science, in press, DOI: 10.1002/pro.2673, 2015.

3.Kazumi Saikusa, Aritaka Nagadoi, Kana Hara, Sotaro Fuchigami, Hitoshi Kurumizaka, Yoshifumi Nishimura, Satoko Akashi.
"Mass spectrometric approach for characterizing the disordered tail regions of the histone H2A/H2B dimer."
Analytical Chemistry, 87, 2220-2227 (2015).

4.Satoko Akashi, Simin D. Maleknia, Kazumi Saikusa, Kebin M. Downard.
"Stability of the βB2B3 crystallin heterodimer to increased oxidation by radical probe and ion mobility mass spectrometry."
Journal of Structural Biology, 189, 20-27 (2015).

2013

5.Nanako Azegami, Kazumi Saikusa, Yasuto Todokoro, Aritaka Nagadoi, Hitoshi Kurumizaka, Yoshifumi Nishimura, Satoko Akashi.
“Conclusive evidence of the reconstituted hexasome proved by native mass spectrometry”
Biochemistry, 52, 5155-5157 (2013). (Highlight Article)

6. Kazumi Saikusa, Sotaro Fuchigami, Kyohei Takahashi, Yuuki Asano, Aritaka Nagadoi, Hiroaki Tachiwana, Hitoshi Kurumizaka, Mitsunori Ikeguchi, Yoshifumi Nishimura, Satoko Akashi.
“Gas-phase structure of the histone multimers characterized by ion mobility mass spectrometry and molecular dynamics simulation”
Analytical Chemistry, 85, 4165-4171 (2013).

7. Kazumi Saikusa, Naoyuki Kuwabara, Yuichi, Kokabu, Yu Inoue, Mamoru Sato, Hiroshi Iwasaki, Toshiyuki Shimizu, Mitsunori Ikeguchi, Satoko Akashi.
“Characterisation of an intrinsically disordered protein complex of Swi5–Sfr1 by ion mobility mass spectrometry and small-angle X-ray scattering”
Analyst, 138, 1441-1449 (2013).

2010
8.Kazumi Saikusa, Yo Kono, Shunsuke Izumi.
"Topology and dynamics of melittin within the liposome revealed by a combination of mass spectrometry and chemical modification"
Biochemical and Biophysical Research Communications, 397, 1-4 (2010).

総説・解説


1. 明石　知子、七種　和美
「タンパク質複合体のイオンモビリティ質量分析」
エアロゾル研究, 28巻, 119-124 (2013).

2. 七種　和美
「一細胞質量分析法を用いた細胞内薬物代謝分析」
日本薬学会ファルマシア, 48 (12), (2012).

3. 七種　和美、河野　陽、泉　俊輔
「質量分析と化学修飾を用いた膜貫通ヘリックスの膜内ダイナミクス解析」
Journal of the Mass Spectrometry Society of Japan, 58号, 75-79, (2010).

国際学会における口頭発表


1. Kevin Downard, Satoko Akashi, Kazumi Saikusa, Simin Maleknia.
“Stability of the βB2B3-beta crystallin heterodimer to increased oxidation by radical probe and ion mobility mass spectrometry”
20 th International Mass Spectrometry Conference, Geneva, Aug 24- Aug 29, 2014.

2. Kazumi Saikusa, Sotaro Fuchigami, Kyohei Takahashi, Yuuki Asano, Aritaka Nagadoi,
Hiroaki Tachiwana, Hitoshi Kurumizaka, Mitsunori Ikeguchi, Yoshifumi Nishimura, Satoko Akashi.
“What happens on the histone multimers in the gas phase? ”
19 th International Mass Spectrometry Conference, Kyoto, Sep 15- Sep 21, 2012.

3. Kazumi Saikusa, Naoyuki Kuwabara, Yu Inoue, Yuichi Kokabu, Mamoru Sato, Hiroshi Iwasaki, Mitsunori Ikeguchi, Toshiyuki Shimizu, Satoko Akashi(発表者).
“Behavior of intrinsically disordered regions within a protein complex of Swi5-Sfr1 characterized by IM-MS and SAXS”
19 th International Mass Spectrometry Conference, Kyoto, Sep 15- Sep 21, 2012.

国際学会におけるポスター発表


1. Kazumi Saikusa, Aritaka Nagadoi, Kana Hara, Sotaro Fuchigami, Hitoshi Kurumizaka, Mitsunori Ikeguchi, Yoshifumi Nishimura, Satoko Akashi.
“Behavior of the disordered tail regions of the histone H2A/H2B dimer”
20 th International Mass Spectrometry Conference, Geneva, Aug 24- Aug 29, 2014.

2. Satoko Akashi, Nanako Azegami, Kazumi Saikusa, Yasuto Todokoro, Aritaka Nagadoi, Hiroshi Kurumizaka, Yoshifumi Nishimura.
“Native Mass Spectrometry of Reconstituted Human Nucleosome Core Particle”
20 th International Mass Spectrometry Conference, Geneva, Aug 24- Aug 29, 2014.

3. Kazumi Saikusa, Sotaro Fuchigami, Kyohei Takahashi, Yuuki Asano, Aritaka Nagadoi, Hiroaki Tachiwana, Hitoshi Kurumizaka, Mitsunori Ikeguchi, Yoshifumi Nishimura, Satoko Akashi.
“Structural Characterization of the histone multimers in the gas phase using ion mobility mass spectrometry and molecular dynamics simulation”
58th Annual Meeting of the Biophysical Society, San Francisco, Califonia, February 15 – February 19, 2014.

4. Kazumi Saikusa, Sotaro Fuchigami, Yuuki Asano, Aritaka Nagadoi, Hiroaki Tachiwana, Hitoshi Kurumizaka, Mitsunori Ikeguchi, Yoshifumi Nishimura, Satoko Akashi.
“Structure of histone H2A/H2B dimer analyzed by ion mobility mass spectrometry and molecular dynamics simulation”
Proceeding of the 61th ASMS Conference on Mass Spectrometry and Allied Topics, Mineapolis, Minesota, June 10 – June 13, 2013.

5. Kazumi Saikusa, Naoyuki Kuwabara, Yuichi Kokabu, Mamoru Sato, Hiroshi Iwasaki, Mitsunori Ikeguchi, Toshiyuki Shimizu, and Satoko Akashi.
“Behavior of intrinsically disordered regions within a protein complex of Swi5-Sfr1 characterized by ion mobility mass spectrometry”
Proceeding of the 60th ASMS Conference on Mass Spectrometry and Allied Topics, Vancouver, Canada, May 20 – May 24, 2012.

6. Kazumi Saikusa, Susumu Yoshioka, Shunsuke Izumi.
“A mechanism of the c ions formation involving the “Gly-ization” of the Thr side-chain in melittin in MALDI-QIT-TOF MS”
Proceeding of the 59th ASMS Conference on Mass Spectrometry and Allied Topics, Denver, Colorado, June 6 – June 9, 2011.

7. Kazumi Saikusa, Yo Kono, Shunsuke Izumi.
“The membrane topology and the dynamics of melittin within the liposomes”
Proceeding of the 57th ASMS Conference on Mass Spectrometry and Allied Topics, Philadelphia, Pennsylvania, May 31 – June 4, 2009.

8. Kazumi Saikusa, Shunsuke Izumi, Toshifumi Hirata.
“Mechanism of the insertion of bilayer membrane by melittin”
Proceeding of the 55th ASMS Conference on Mass Spectrometry and Allied Topics, Indianapolis, Indiana, June 3 – June 7, 2007.

受賞等


・平成26年度（2014年度）　広島大学女性研究者奨励賞
・2009年度　日本質量分析学会　BMS研究会　BMSトラベルアワード
・2006年度　日本化学会　中国四国支部　支部長賞
・第2回　ナノインフォ化学シンポジウム　学生賞